Adaptation

So I got the first wrench (probably not the last) thrown into my plans yesterday.  Got a call from the Doc stating that I am not eligible for the OGX-427 study I had chosen after careful contemplation.  The issue was that my most recent BCG treatment was done in the last 3 months.  The frustrating part is that this was known during our consultation last week so I should have not been given the option, seems like the exception was in the fine print.  On the other hand, the clinical trial was in a 50/50 coin toss with a treatment called High Dose Intensity MVAC (HD-MVAC).  With the trial eliminated, the options were really HD-MVAC or straight GC (the two standard drugs used in the trial).  After looking over some studies again (referenced below) I have chosen to go with the HD-MVAC.  This will be a 14-day cycle with drugs given on days 1 and 2.

MVAC vs. HD-MVAC

MVAC vs. GC

Goal: Complete Response
Logic: MVAC = GC for complete response, HD-MVAC > MVAC for complete response, thus HD-MVAC is our champion!

This is considered a standard treatment and not a trial so on the plus side we get to start soon, as in next week, on Halloween!  So do I dress up for my first dose of chemo?